Chronic Joint Disease

Why does chronic inflammatory joint disease persist?

Inflammation is a beneficial host response to tissue damage. Most episodes of inflammation resolve spontaneously and do not persist. However, in rheumatoid arthritis (RA), as in a number of other chronic inflammatory diseases, the inflammatory response persists and a stable inflammatory infiltrate accumulates in the joint. What drives this persistence and the relative contribution of infiltrati...

On a form of chronic joint disease in children. 1896.

CHRONIC RHEUMATIC JOINT DISEASE IN GENERAL PRACTICE.* By PHILIP

Chronic rheumatic joint disease is the greatest single cause of disability in temperate climates and is said to produce more pensionable invalidism than any other condition except cardiovascular disease in old age. It is therefore unfortunate that chronic arthritis, which is so formidable a scourge in this country, should, until recent years, have been relegated to the list of uninteresting and...

On a Form of Chronic Joint Disease in Children

Rubella virus and chronic joint disease: is there an association?

Synovial fluid samples and/or biopsies from 79 patients with various chronic inflammatory joint diseases or traumatic joint injury were tested for rubella virus (RV) in order to confirm or refute results from other studies that suggested RV as a cause of chronic inflammatory joint disease. Sixty-eight of the 72 patients tested had RV antibodies. RV RNA was detected by reverse transcription-PCR ...